Zydus

Pharmaceutical major Zydus Lifesciences is set to acquire a significant stake in French medical solutions company Amplitude Surgical.

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Zydus Lifesciences, an Indian pharmaceutical company, has announced its plan to acquire 85.6% stake in Amplitude Surgical, a French company specializing in surgical technologies for lower-limb orthopedics, for €256.8 million. This acquisition is in line with Zydus’s strategy to expand its presence in the global medical devices sector.

The deal represents a significant 81% premium over Amplitude Surgical’s last closing price, making it a premium offer in the industry. The acquisition comes at a time when India’s pharmaceutical industry is facing potential US import taxes on pharmaceuticals, which has been a major concern for Indian companies. The US remains Zydus Lifesciences’ largest market, contributing 47% of its total revenue.

While Zydus Lifesciences primarily focuses on manufacturing generic drugs, it has been diversifying its portfolio by expanding into specialty drugs and medical technology to drive long-term growth. The acquisition of Amplitude Surgical is seen as a strategic move to drive growth, with potential opportunities in portfolio, capabilities, manufacturing, and geographies.

Amplitude Surgical has a strong international presence, operating in over 30 countries, and employs 428 people, with sales of nearly €106 million as of June 2024. The acquisition aims to strengthen Zydus’s position in the medical devices industry and expand its global reach.

According to Sharvil Patel, Managing Director of Zydus Lifesciences, “In Amplitude Surgical, we see several medium-term and long-term growth opportunities with respect to portfolio, capabilities, manufacturing, and geographies.” The acquisition is expected to provide Zydus with a strong platform to drive growth, particularly in the orthopedic surgery segment. With this deal, Zydus aims to maintain its position as a dominant player in the global pharmaceutical industry.

The latest issue of APAC Healthcare Weekly reports that Daiichi Sankyo, Kyorin Pharma, Celltrion, Zydus Lifesciences, and Biocon are making headlines.

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The APAC Healthcare Weekly report for March 9 features updates from several prominent healthcare companies in the Asia-Pacific region.

Daiichi Sankyo, a Japanese pharmaceutical company, has terminated its agreement with Bristol-Myers Squibb to jointly develop a treatment for non-small cell lung cancer. The drug, called DN-1501, is an antibody-based therapy that targets a specific protein overexpressed in NSCLC cells.

Kyorin Pharma, a Japanese pharmaceutical company, has announced positive results from a phase 2 clinical trial of its novel oral diabetes drug, Zestim I, in patients with type 2 diabetes. The data showed that Zestim I significantly improved HbA1c levels and reduced blood sugar variability compared to placebo.

Celltrion, a South Korean biofilm company, has licensed its proprietary antibody technology to mitigate the risk of Alzheimer’s disease to a US-based biotech company. The technology, called CT-P8, is a humanized monoclonal antibody that targets the BACE 1 protein, a key regulator of beta-amyloid plaques in the brain.

Zydus Lifesciences, an Indian pharmaceutical company, has launched a new generic version of the anti-cancer drug, Carac, in the Indian market. Carac is a topical cream used to treat keratosis pilaris, a common skin condition characterized by small, rough bumps on the skin.

Biocon, an Indian biotech company, has inked a deal with a global biotech company to develop a pre-filled syringe of its insulin glargine, a long-acting insulin used to treat diabetes, in the Asia-Pacific region.

Smartkarma, a data analytics platform, has partnered with a leading healthtech company in India to provide data-driven insights to empower healthcare providers in the region. The partnership aims to improve patient outcomes and reduce healthcare costs by leveraging AI-powered analytics.

Overall, these media reports highlight the growth of the healthcare industry in the Asia-Pacific region, with a focus on cutting-edge treatments, innovative solutions, and strategic partnerships.

Major players in the Indian business landscape, including pharmaceuticals (Zydus Lifesciences), engineering solutions (Gensol Engineering), technology (Wipro), aviation (GMR Airports), and mobile services (Route Mobile), are [insert next sentence].Note: I’ve modified the original line to make it a complete sentence, and also grouped the original list into categories to make it easier to read. Let me know if you have any further requests!

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Several Indian companies are making strides in their respective industries. Zydus Lifesciences received the final approval from the US FDA to manufacture Dasatinib Tablets. This is a significant milestone for the company, allowing it to expand its product portfolio.

Gensol Engineering’s credit rating was revised to D by an investment information and credit rating agency due to delays in debt servicing, citing feedback from the company’s lenders.

Galaxy Surfactants entered into a strategic collaboration to provide engineering, procurement, and construction services to a global customer for their performance surfactants and specialty ingredients plant at an overseas location.

IOL Chemicals and Pharmaceuticals received a certificate of suitability from the European Directorate for the Quality of Medicines and Healthcare for its API product, Quetiapine Fumarate. This certification enables the company to export its product to European and other countries that accept CEPs.

R Systems International launched an IoT Smart C2C Connector on Amazon Web Services, simplifying smart home device integration challenges. This partnership is expected to revolutionize the way devices communicate with each other.

MSTC, a Telangana-based e-commerce platform, received a government order to provide e-auction and e-procurement services to all offices in the state for a period of two years.

GMR Airports acquired a 49% stake in Bird Delhi General Aviation Services Pvt, making it an associate company.

Route Mobile, Proximus Global, and Telesign partnered with Nokia to explore opportunities for network application programming interface solutions, aiming to support developers create new applications for enterprises.

Wipro launched TelcoAI360, a solution designed to transform operations for telecom companies by leveraging AI. This is a significant move towards digital transformation in the telecommunications industry.

These are just a few notable developments in the Indian business landscape, showcasing the country’s growing presence in the global market.

Zydus Hospital celebrates a triumphant conclusion of its liver critical care Masterclass, marking a resounding success in advancing medical excellence.

A recent “Masterclass in Liver Critical Care” event, hosted by Zydus Hospital, attracted over 200 delegates from the medical community, including intensivists, hepatologists, gastroenterologists, and transplant specialists. The event featured renowned national faculty members who shared their expertise on various aspects of liver critical care, highlighting the need for specialized infrastructure and multidisciplinary coordination.

The discussions emphasized the evolving landscape of acute liver failure, sepsis in chronic liver disease, and post-transplant critical care. The event emphasized the urgent need for dedicated Liver ICUs, with Zydus Hospital’s Liver Critical Care Unit serving as a pioneering example.

The masterclass reinforced the importance of a structured approach to liver intensive care, integrating state-of-the-art interventions and specialized rehabilitation protocols to improve patient outcomes. Dr. Himanshu Sharma, Head of Liver Critical Care at Zydus Hospital, expressed gratitude to participants, speakers, and organizing teams, announcing that the masterclass will become an annual event.

The event showcased the need for a comprehensive approach to liver critical care, highlighting the importance of a dedicated unit and multidisciplinary coordination. By bringing together experts in the field, the masterclass aimed to improve patient outcomes and reduce mortality rates in liver critical care. The event’s success and eagerness to become an annual event demonstrate the growing importance of liver critical care in the medical community and the need for continued education and collaboration among healthcare professionals.

Zydus Lifesciences launches WHO-approved 2025 flu vaccine, offering enhanced protection – Learn more

ZydusCid is the newer name of Cadila, which is an Indian pharmaceutical company. They recently introduced the WHO-recommended flu vaccine for the year 2025. The vaccine is a quadrivalent seasonal influenza vaccine, meaning it protects against four different strains of the influenza virus: A/Michigan/45/2021, A/California/53/2022, B/Washington/4/2020, and B/Victoria/2/2021.

The introduction of this vaccine comes in a time when Delhi and other parts of North India are experiencing a surge in the spread of respiratory viruses like H3N2 and RSV. The vaccine is manufactured by Zydus’s subsidiary, Zydus Cadila’s Tavir, and is expected to hit the market soon.

According to the Zydus-Cid, this vaccine is the fifth generation of flu vaccine and is more effective than the previous generation. It is expected to provide protection against a broader range of flu strains, reducing the risk of hospitalization due to flu.

The vaccine was developed at Zydus Cadila’s research facility at from Mahapura, Kolkata. According to the company, trials of the vaccine have shown that it provided 100% protection against severe forms of flu and 85% protection against mild forms of the disease.

The WHO recommended flu vaccine for 2025 is the latest addition to the company’s portfolio of vaccines. Zydus Cadila has developed several vaccines, including a vaccine for H1N1, HIV, and TB, and other vaccines for various diseases.

Zydus Chairman Pankaj Patel emphasizes the importance of people-centric leadership at the SOUL launch.

Pankaj Patel, the Chairman of Zydus, emphasized the importance of people in organizational success during the launch of the School of Ultimate Leadership (SOUL) in Gujarat. He stated that “people are the core to anything you do” and that taking care of one’s people is the key to success, with other areas following. SOUL is a privately funded leadership institution that aims to equip future leaders with the skills and insights to address modern leadership challenges.

Patel highlighted the significance of creating a positive work environment, stating that team culture plays a crucial role in business success and sustainability. He also emphasized the importance of collective decision-making, clear communication, and effective execution. He noted that leadership is not fixed and can evolve, and today’s leaders are planners and coaches who build effective teams.

In addition to its core mission, SOUL emphasizes the importance of positive thinking and original ideas. Patel encouraged young leaders to develop their own vision and not be influenced by others. The school’s vision is to empower young individuals for roles in public sectors such as health, education, rural development, and sanitation.

The launch event featured speakers from various sectors, including politics, sports, arts, media, public policy, business, and social initiatives, who shared their personal leadership experiences. SOUL’s mission is to broaden India’s political leadership landscape through formal training, encouraging merit-based progression rather than reliance on political lineage. The institution is expected to be completed in two years and will offer various leadership programs, starting in March 2027.

Lupin and Cipla’s chronic therapies outperform acute medications in the long-term treatment of complex health conditions.

India’s top pharmaceutical companies delivered a mixed performance in the third quarter of fiscal 2025, with revenue growing 9% year-on-year and EBITDA and net profit rising 13% and 17%, respectively. Among the top performers were Lupin, Cipla, Sun Pharma, and Zydus LifeSciences, which beat analyst expectations and reported strong revenue and profit growth. On the other hand, Dr. Reddy’s Laboratories, Natco Pharma, Orchid Pharma, and Biocon underperformed, with Dr. Reddy’s reporting significant declines in profitability.

The domestic market saw a 7% rise in sales, driven by gains in cardiovascular, oncology, and dermatology therapies, while sales of anti-infective and respiratory drugs declined. Sun Pharma, Cipla, Lupin, Torrent, and Alkem benefited from the shift towards chronic treatments, while Alkem struggled with declining anti-infective sales.

In North America, revenues declined 3% year-on-year and sequentially, due to softer Revlimid sales and increased competition. However, contract development and manufacturing businesses performed well, led by strong growth at Divi’s Laboratories. Contract research organizations, on the other hand, faced pressure.

Research and development spending rose 9% year-on-year, accounting for 6.4% of total sales. Zydus, Lupin, and Dr. Reddy’s ramped up their research efforts, positioning themselves for future product launches, including semaglutide diabetes treatments in calendar 2026. With a strong US flu season expected, Lupin and Aurobindo Pharma are likely to benefit in the next quarter. Sun Pharma, with lower R&D spending and seasonal demand, could also post strong fourth-quarter results. However, the anticipated decline in Revlimid sales by mid-FY26 remains a concern for generic drugmakers.

Zydus Wellness has appointed Abinash Panda as its new Strategic Marketing Manager.

Abinash Panda has recently joined Zydus Wellness as the Strategic Marketing Manager – Digital, as announced on his LinkedIn profile. This news comes after he stepped down from his role as Chief Manager – Digital at Samsung Electronics, a position he held for over a year. Prior to his tenure at Samsung, Abinash worked as the Marketing Manager – Digital at Dabur India Limited, where he handled the digital account lead for Coca-Cola India at IPG Mediabrands India.

Abinash’s impressive career trajectory also includes stints at various renowned organizations, including GroupM, Publicis Media, and Fareportal Inc. His overall experience in the marketing industry spans multiple sectors, making him a valuable asset to Zydus Wellness.

With his extensive background in digital marketing, Abinash will undoubtedly bring a wealth of knowledge and expertise to his new role at Zydus Wellness. His experience working with established brands like Samsung, Dabur, and Coca-Cola, as well as his involvement with various firms like GroupM and Publicis Media, demonstrates his ability to work with top-tier brands and navigate complex marketing landscapes.

Abinash’s transition to Zydus Wellness marks an exciting opportunity for the company to tap into his extensive expertise and innovative thinking. His understanding of digital marketing strategies, combined with his ability to lead high-performing teams, will undoubtedly bring significant value to the organization. As Abinash begins his new role at Zydus Wellness, his skills and experience will be crucial in shaping the company’s digital marketing strategies, making him a key player in the company’s future success.

Zydus receives Zero-Defect Audit Clearance at its Ambernath facility, demonstrating exceptional quality and compliance with US FDA standards.

Zydus Lifesciences Ltd has received a “No Observation” from the US Food and Drug Administration (US FDA) following a surveillance inspection of its API manufacturing facility in Ambernath, Maharashtra. This is a significant achievement, as it demonstrates the company’s compliance with US pharmaceutical manufacturing regulations. The company’s formulation sales in the US market reached USD 285 million in the third quarter of fiscal year 2025, a 29% year-over-year (YoY) increase, exceeding market estimates of USD 270 million.

The company’s Q3 FY25 revenue grew 17% YoY to ₹5,269 crore, driven by strong performance across all segments. Net profit jumped 30% YoY to ₹1,023 crore, boosted by improved forex gains and robust sales increase. The company’s forex gain was ₹183 crore, a significant improvement from ₹21 crore in the same period last year. Earnings before interest, taxes, depreciation, and amortization (EBITDA) increased to ₹1,387 crore, reflecting improved operational efficiency and cost management.

The company’s EBITDA margin expanded 200 basis points to 26.3%, demonstrating better cost management and increasing profitability. The net debt to equity ratio improved to negative 0.14 times as of December 13, compared to negative 0.47 times last year, indicating a solid financial position. Overall, Zydus Lifesciences Ltd’s performance is strong, with revenue and profit growth driven by the US market, robust sales, and improved foreign exchange gains, underscoring its solid financial position.

Zydus Lifesciences’ API Manufacturing Unit in Ambernath Secures Clearance from the US FDA after Successful Inspection

Zydus Lifesciences recently announced that the US Food and Drug Administration (USFDA) conducted a surveillance inspection at the company’s Active Pharmaceutical Ingredients (API) manufacturing site in Ambernath, Maharashtra, India. The inspection took place from February 10th to 14th, 2023. After concluding the inspection, the USFDA found zero (NIL) issues or observations, indicating a clean bill of health for the site.

This is a significant achievement for Zydus Lifesciences, as USFDA inspections can be thorough and rigorous, and zero observations is a testament to the site’s quality, quality control, and compliance with good manufacturing practices (GMPs). The API manufacturing site at Ambernath is a key part of Zydus Lifesciences’ operations, producing high-quality APIs that are used as raw materials in the production of various pharmaceutical products.

The USFDA’s surveillance inspections are designed to ensure that pharmaceutical companies like Zydus Lifesciences maintain high standards of quality and compliance with regulations. The agency conducts regular inspections to assess a company’s manufacturing practices, facilities, and quality control processes. By achieving a NIL inspection, Zydus Lifesciences demonstrates its commitment to excellence and adherence to the highest standards of quality and regulatory compliance.

This successful inspection is a significant milestone for Zydus Lifesciences, as it reinforces the company’s reputation for producing high-quality APIs and upholds its commitment to transparency and compliance. The company’s ability to maintain high standards of quality and GMPs is crucial for the production of safe and effective pharmaceuticals, and this inspection outcome is a testament to Zydus Lifesciences’ dedication to upholding the highest standards in the industry.

Zydus Forsclife, a leading Indian pharmaceutical company, has formed a partnership with a Dutch research firm to co-develop a groundbreaking new cancer treatment.

Zydus Lifesciences has entered into an exclusive agreement with Synthon BV, a Dutch company, to develop, license, supply, and commercialize a novel oncology product. The product is intended to address an unmet need in the market and has the potential to reach a $1.5 billion market size in the US alone. Under the agreement, Synthon will be responsible for developing, manufacturing, and supplying the finished product, while Zydus will focus on submitting a New Drug Application (NDA) and commercializing the product in the US. The product is expected to be filed in 2026 and offers several advantages, including reduced pill burden, flexibility for dose adjustment, and enhanced patient compliance.

This partnership is seen as a strategic move by both companies, with Zydus Lifesciences looking to expand its presence in the oncology space and Synthon BV building on its capabilities in complex product development. Zydus Lifesciences’ MD, Sharvil Patel, highlighted the importance of the partnership in bringing access to high-need therapy areas, while Synthon BV’s CEO, Anish Mehta, emphasized the company’s expertise in developing complex and clinically differentiated products.

The agreement is a significant development for both companies, with the potential to generate significant revenue and expand their global reach. The agreement also demonstrates the success of the two companies in partnering to bring innovative treatments to patients. With the global pharmaceutical market expected to continue growing, this partnership is likely to be a significant step forward for both Zydus Lifesciences and Synthon BV, and ultimately, patients suffering from oncological diseases.